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BJ said:Would you be kind enough to share the brand?  Thanks.  BJ

This question was not directed to me, but DSM makes  a synthetic resveratrol called ResVida. It is 98-99% pure and a study was published showing that it appears to be safe, nontoxic, and nonmutagenic in animals:

1. Food Chem Toxicol. 2009 Sep;47(9):2170-82. Epub 2009 Jun 6.

Safety studies conducted on high-purity trans-resveratrol in experimental

animals. Williams LD, Burdock GA, Edwards JA, Beck M, Bausch J.

Burdock Group, Orlando, FL 32801, USA.

"trans-Resveratrol is a naturally occurring polyphenolic compound found in a

variety of foods, but predominantly in grapes. Safety studies were conducted on

high-purity trans-resveratrol (Resvida), including skin and eye irritation,

dermal sensitization, subchronic and reproductive toxicity, genotoxicity, and

absorption, metabolism and excretion. Resvida was non-irritating to skin and eyes

and non-sensitizing. It was non-mutagenic in a bacterial reverse mutation assay

in Salmonella typhimurium and Escherichia coli, but exhibited clastogenic

activity in a chromosomal aberration test in human lymphocytes. However, in an in

vivo bone marrow micronucleus test in rats, Resvida was non-genotoxic. In a

28-day study, Resvida caused no adverse effects in rats at 50, 150 and 500 mg/kg 

bw/day. Similarly, in a 90-day study, Resvida did not cause any adverse effects

in rats at up to 700 mg/kg bw/day; the highest dose tested. Resvida did not

induce any adverse reproductive effects in an embryo-fetal toxicity study in rats

at a dose of 750 mg/kg bw/day. Also, in vitro and in vivo absorption, metabolism,

and excretion studies in Caco-2 cells, rat primary hepatocytes and male and

female rats (in vivo) show that Resvida is readily absorbed, metabolized and

excreted. These studies provide evidence that Resvida is well tolerated and

non-toxic."

Of course, mice are not people and long-term safety is still unknown. It appears that the study was conducted by a consulting firm at the request of the manufacturer. It doesn't mean the results are invalid, but just something to keep in mind.