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Post edited 2:55 am – July 21, 2010 by FM2020

Resveratrol was found to be effective to an extent against pre-diabetes this spring, but a "preliminary result."

"It is a small study and needs to be confirmed, as other studies with this drug have been negative," Vivian Fonseca, MD, of Tulane University, told MedPage Today.

For their study, the researchers recruited 10 patients ages 60 to 80 who had impaired glucose tolerance.

Over four weeks, patients took one of three doses of resveratrol (1g, 1.5g, or 2g) with a standard meal that included 110 grams of carbohydrates, 20 grams of protein, and 20 grams of fat."

The researchers said the results didn't vary by dose, so they combined the data for the analysis.

 [This is good news since it provides evidence that 1g of resveratrol is as good as 1.5g or 2g, so a person can take less for pre-diabtes. The next larger study should try 250mg, 500mg and 1000mg] 

"She and colleagues found that after four weeks of resveratrol supplements, fasting plasma glucose was unchanged, but both peak post-meal glucose and three-hour glucose area under the curve declined (185 mg/dL versus 166 mg/dL, and 469 versus 428, respectively, P=0.001)."