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How much resveratrol shoudl I take?

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10:37 am
November 12, 2009


RevGenetics

Member

posts 93

Post edited 1:29 pm – December 1, 2009 by RevGenetics


I am simply informing folks that we have different products.

  • We have regular resveratrol, like everyone else has.
  • We also have Micronized resveratrol at 1.5 microns, that no one else produces.

These are simple facts.


Micronization is used in pharmaceuticals to increase absorption and sometimes bioavailability. We use it to help increase absorption. We also point out that we are the only folks who provide micronized resveratrol powder. These also are simple facts. 


Resveratrol is not soluble. Many folks can open up a resveratrol supplement capsule from any manufacturer and place the dry powder from the capsule into a glass of water at the kitchen table, to test this out. For most of us who have been taking resveratrol for years, this is common sense and does not need to be explained.


So what other things are needed to be done to increase absorption? One of them is micronization. Micronization is not new, it is one of the ways to increase absorption. Don't take my word for it, see links below that explain it:


http://journals.prous.com/jour…..p;p_IsPs=N

http://grande.nal.usda.gov/ibi…..row=762296


Regarding resveratrol absorption, we can only look at the charts made public by Sirtris regarding absorption. If other folks can show a different study that shows different data (other than that of the Sirtris animal data), we would love to see the data.

I am sure the company would then be a candidate to be bought out by Glaxo-Smith Kline for such an important observation that Sirtris would have missed entirely. However, I don't think anyone disputes Sirtris data at this time.


Do you dispute the Sirtris charts? If so, please explain why.

A

8:47 am
November 12, 2009


FM2020

Member

posts 82

RevGenetics,

There is no scientific basis for you to claim that your micronized product is superior to Biotivia. That it is 1.5 microns across means nothing until you or others can show this provides greater bioavailablity than other resveratrol products.

9:56 pm
November 11, 2009


RevGenetics

Member

posts 93

Post edited 10:51 pm – November 11, 2009 by RevGenetics



It seems the last post needs clarification:

RevGenetics offers regular high purity resveratrol found in our X500 capsules which was compared to Biotivia's old Transmax by using an electron microscope by a third party back in early 2008. Both products had large particle sizes typically found in supplements. Our product compared was this one: RevGenetics X500 our 500mg Resveratrol supplement


However, since then we, we started to provided new Micronized Resveratrol that was independently verified by The Florida Center for Analytical Electron Microscopy: http://www.fiu.edu/~emlab/home.html. We consider this micro resveratrol, some of the best powder available for the public.


At this time, no one else offers resveratrol powder with an average particle size of 1.5 microns. We offer it in bulk powder, 250mg & 500mg capsules. If you click on the micronized resveratrol link, you can see that there is quite a difference in particle size in the SEM pictures.


Some folks say that resveratrol has saved their life (Schizoaffective Bipolar Disorder) which I found interesting. Personally I have just felt a feeling of well being at 1-2 grams. Is it a plcebo effect? Tough to say, but I personally do not think so.  My brother who is obese, tells me he can feel the micronized resveratrol helping him as well, I think he only takes 1000mg. I found that extremely remarkable and asked him to come to Miami and work with me. He now manages the office. My wife took 500mg of the regular X500, got pregnant and stopped (I don't suggest it to new moms who are still breast feeding… simply not enough data), was it coincidence since two doctors said she only had a 5% chance of conceiving? Only more reaserch will be able to tell us.

Hmm… who else? Well my father in law takes it, it maybe amother coincidence, but he plays tennis with folks half his age and beats them regularly… he is retired and in his mid 60's. He takes it Resveratrol Nitro250 and Quercetin in equal amounts.

We should have a 250mg Super Curcumin capsule in December, due to the recent study regarding resveratrol and Curcumin. I am going to ask my father in law to take it. Last but not least we will have a P16 activator soon from an herbal source… this one is not for everyone, but will ask my own father to take it along with our other products… he is in his 70's.

Again, this is just personal information, in no way does this constitute as advice for anyone. These personal statements I shared with you all have not been evaluated by the Food and Drug Administration. You have to always keep in mind that resveratrol and other supplement products are not intended to diagnose, treat, cure or prevent any disease.

Cheers

A

8:32 pm
November 11, 2009


FM2020

Member

posts 82

Post edited 8:44 pm – November 11, 2009 by FM2020


2tender said:Agreed, the high emodin content of most products is what made a lot of people stop taking it. The lay public does'nt realize that all Resveratrol is not created equally and that factors such as purity, emodin, micronization,level of dose, all can make a world of difference in results. People think Resveratrol is Resveratrol, but there is a distinct difference in quality and type.

Some products are essentially identical as can be seen under the microscope on a thread at the Immortality Institute. Two that were compaed were Biotivia and RevGenetics looked identical except for a small variance in crystal size. The brand Dr. Sinclair took for several years is somewhat different because it contains two other compunds as well.


In addition, I know people who have stopped taking resveratrol because they didn't like some side effect. This is true for one taking at 500mg but I know two who stopped at 100mg as well. Both were 98% pure and did not contain emodin.

People have had different experiences with resveratrol and one who decides to take it should be aware of potential unpleasant side effects. I had a strange sensation as did a friend, but in both cases it was gone the next day and didn't return.

7:19 pm
November 11, 2009


2tender

USA

Member

posts 51

Agreed, the high emodin content of most products is what made a lot of people stop taking it. The lay public does'nt realize that all Resveratrol is not created equally and that factors such as purity, emodin, micronization,level of dose, all can make a world of difference in results. People think Resveratrol is Resveratrol, but there is a distinct difference in quality and type.

5:12 pm
November 11, 2009


RevGenetics

Member

posts 93

Davids said:The e-book download goes into this in detail – it states that the doses based on the mouse studies are 250 -500 mg per day. There are a few reports of resveratrol thinning the blood. I've not read any severe side effects of 1 gram per day.Has anyone had negative side effects we should look for?


Typically I have not seen issues at 2 grams, or 1 gram when taking the pure resveratrol capsules. When taking a 50% resveratrol powder, the emodin in the capsules will likely cause you to become "regular" at the 1 gram to 2 gram dosages. Some older folks like this, while some middle age and younger folks don't.

Because most products don't state how much emodin is contained (which causes this stomach issue), you make find yourself running to the bathroom if the purity and quality of the resveratrol you take is very low, and you try to take 1-2 grams.


Cheers

A

5:59 pm
November 8, 2009


2tender

USA

Member

posts 51

Post edited 6:05 pm – November 8, 2009 by 2tender


 Sounds about right, depends on the size of the simian, if they're chimpanzees though, there could be a difference. I feel best with between 500 mgs and an approximate gram daily. I cant get an accurate measure on how much Im absorbing through the Transdermal  lotion, so Ive cut back on that to less than daily dosing and added 250 mgs of pre-emulsified Quercetin in a Licap, ingested simultaneously with the 250 mgs of pre-emulsified Resveratrol in a licap, and a capsule of RLA/RDHLA/ Tocotrienol that is swallowed with water or juice which contains an approximate 300 mgs of  micronized, 98% pure powdered Resveratrol, the same amount of a tocotrienol powder, 3 grams of glutamine, 3 grams of creatine and 15 grams of whey protein isolate, mixed into it. So you say the monkeys arent getting sick? Hmmm…

4:08 am
November 4, 2009


motie2

Member

posts 7

Resforum tweet today – monkeys on 480 mg of resveratrol show cardioproteciton and less diabetes in NIH study. In humans, Im guessing this would be about a gram a day??

10:50 am
October 31, 2009


2tender

USA

Member

posts 51

After taking Resveratrol for approximately a year, in various forms, I would say that from 250 mgs to 1 gram or slightly under a gram, seems to be adequate for people in reasonable health. I think its important to use the highest purity, low emodin content, micronized, product available. There is a pre-emulsified capsule available that is popular. Im taking between 500 and 700 mgs daily by using a transdermal lotion, pre-emulsified cap and micronized powder mixed in juice. 

6:16 pm
October 30, 2009


trabie

Member

posts 4

The mice in the amazing new colon cancer study (see reforum tweet) took 30 mg.kg.2days, which by may calculation is only about 250 mg every 2 days for a human. That's great news cause thats how much I take (with breakfast and milk to increase absorption).

3:36 pm
October 29, 2009


Davids

Member

posts 4

The e-book download goes into this in detail – it states that the doses based on the mouse studies are 250 -500 mg per day. There are a few reports of resveratrol thinning the blood. I've not read any severe side effects of 1 gram per day.Has anyone had negative side effects we should look for?

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