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There  is an interesting review of bioavailability of resveretrol on Wikipedia.  Taking resveretrol with red wine did not seem to increase blood levels.  Taking it with food does seem to help.  The melting point is 256 degrees C so it is a solid at body temp and does not dissolve in water, only in pure alcohol.  Personally, I think there is good evidence that taking a micronized, or emulsified form of resveretrol is the best method of reaching adequate blood levels.  I have found the same thing to be true of CoQ-10 which is a wax that melts at 108 F — still way above normal body temperature.  I tried melting it in a very hot drink with cream (or coconut milk) and still found considerable residue in the bottom of the cup.  The other suggested delivery method is holding it in the mouth — but this stuff is very irritating and tastes terrible.